Example of channel system of 1JJ2
MOLE 2 is a successor of a popular software tool
Mole for detection and characterization of channels in biomacromolecules (proteins, nucleic acids and glycans). This completely redesigned version allows user rapid and accurate
analysis of channels and transmembrane pores even
in large structures (hundreds of thousands of atoms). As a new feature, MOLE 2
estimates not only
physicochemical properties of the identified channels, i.e.,
hydropathy, hydrophobicity, polarity, charge, and mutability, but also physicochemical properties of the cavities. For thorough description of the functionality and instructions on working with MOLE 2 please consult the
paper or our
manual.
MOLE 2.5 Update
Update of MOLE 2 ..→